Harlequins prop Joe Marler and Wasps lock Joe Launchbury have withdrawn from England’s Six Nations squad.
Launchbury is out through injury, with a stress fracture to his leg, while Marler has withdrawn for personal reasons.
Bath second row Charlie Ewels and Wasps loose-head Tom West will join up with the squad when they gather on Wednesday.
England open their Six Nations campaign against Scotland on 6 February.
