England forward Courtney Lawes will be unavailable for the rest of the Six Nations because of a pectoral injury.
Northampton’s Lawes was ruled out of Saturday’s game against Wales after falling during training on Wednesday.
The 32-year-old missed England’s autumn schedule because of an ankle injury but returned to the starting XV for the side’s Six Nations win against Italy.
“It is very disappointing, but these things happen,” said England attack coach Simon Amor.